About Me

I am a PhD student in Bioinformatics at Boston University, currently working in the Siggers Lab. My research focuses on transcriptional regulation, epigenetics, and computational biology approaches to understand gene regulatory mechanisms. With an M.Sc. and B.Sc. in Biotechnology and Genetic Engineering from Noakhali Science and Technology University, Bangladesh, I bring a perspective that combines wet lab expertise with cutting-edge computational approaches.

My work involves developing innovative computational methods to decode transcriptional regulatory networks, with particular emphasis on chromatin accessibility, transcription factor binding, and epigenetic modifications. I am passionate about bridging experimental biology with computational modeling to advance our understanding of gene regulation and its role in human health and disease.

Education

PhD in Bioinformatics

Boston University
2024 - Present

M.Sc. in Biotechnology and Genetic Engineering

Noakhali Science and Technology University, Bangladesh
2021 - 2023

B.Sc. in Biotechnology and Genetic Engineering

Noakhali Science and Technology University, Bangladesh
2016 - 2020

Research Focus

Computational Genomics

  • ATAC-seq Analysis
  • ChIP-seq Data Processing
  • Single-cell RNA sequencing (scRNA-seq), Cross-Species scRNA Integration
  • Whole Genome Sequencing (WGS)
  • Metagenomics

Systems Biology & ML

  • Transcriptional Regulatory Networks
  • TFs-Cofactor Analysis
  • Convolutional Neural Networks (CNN)
  • Machine Learning Applications
  • Bayesian Modeling
  • Statistical Imputation Methods
  • PPI Biology

Microbial Genomics

  • Comparative Genomics
  • Microbial Community Analysis
  • Functional Annotation
  • Phylogenetic Analysis

Experimental Techniques

  • Protein Purification
  • PCR & qPCR
  • Western Blot Analysis
  • ELISA & TLC
  • Cell Culture (Bacterial & Animal)

Selected Publications

Distinctive genome features of Cutibacterium werkmanii strain NIB003

Hossain, M.S., Rahman, M.M., Islam, M.S., Ahmed, T., Khatun, S., Rahman, M.H.
Gene, Vol. 932, 148965, 2024

Potential Therapeutic Role of Phytochemicals to Mitigate Mitochondrial Dysfunctions in Alzheimer's Disease

Hossain, M.S., Hashimoto, M., Katakura, M., Miwa, K., Shimada, T., Shido, O.
Antioxidants, Vol. 10, No. 1, 23, 2021

Molecular Insights into the Multifunctional Role of Natural Compounds: Autophagy Modulation and Cancer Prevention

Hossain, M.S., Karuniawati, H., Jairoun, A.A., Urbi, Z., Ooi, D.J., John, A., Lim, Y.C., Kibria, K.M.K., Mohiuddin, A.K.M., Ming, L.C., Goh, K.W., Hadi, M.A.
Biomedicines, Vol. 8, No. 11, 517, 2020

Technical Skills

Programming

Python, R, Bash, SQL

Data Management

Computing Clusters, Git, Obsidian

Get In Touch

Location

24 Cummington Mall
Boston University
Boston 02215, MA, USA